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In silico model-guided identification of transcriptional regulator targets for efficient strain design

BACKGROUND: Cellular metabolism is tightly regulated by hard-wired multiple layers of biological processes to achieve robust and homeostatic states given the limited resources. As a result, even the most intuitive enzyme-centric metabolic engineering endeavours through the up-/down-regulation of mul...

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Publicat a:Microb Cell Fact
Autors principals: Koduru, Lokanand, Lakshmanan, Meiyappan, Lee, Dong-Yup
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201637/
https://ncbi.nlm.nih.gov/pubmed/30359263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-018-1015-7
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