FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer’s disease

BACKGROUND: Neurofibrillary pathology composed of tau protein is closely correlated with severity and phenotype of cognitive impairment in patients with Alzheimer’s disease and non-Alzheimer’s tauopathies. Targeting pathological tau proteins via immunotherapy is a promising strategy for disease-modi...

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Veröffentlicht in:Alzheimers Res Ther
Hauptverfasser: Novak, Petr, Schmidt, Reinhold, Kontsekova, Eva, Kovacech, Branislav, Smolek, Tomas, Katina, Stanislav, Fialova, Lubica, Prcina, Michal, Parrak, Vojtech, Dal-Bianco, Peter, Brunner, Martin, Staffen, Wolfgang, Rainer, Michael, Ondrus, Matej, Ropele, Stefan, Smisek, Miroslav, Sivak, Roman, Zilka, Norbert, Winblad, Bengt, Novak, Michal
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201586/
https://ncbi.nlm.nih.gov/pubmed/30355322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0436-1
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