Total Flavone of Rhododendron Improves Cerebral Ischemia Injury by Activating Vascular TRPV4 to Induce Endothelium-Derived Hyperpolarizing Factor-Mediated Responses

BACKGROUND: Total flavonoids of Rhododendron (TFR) is extracted from Rhododendron, a herbal medicine widely used in China. The main components are flavone compounds such as warfarin, rutin, quercetin, and hyperoside. We investigated the role of TRPV4 channel in the TFR induced endothelium-dependent...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Han, Jun, Xu, Hang-Hang, Chen, Xiao-Long, Hu, Hao-Ran, Hu, Kun-Mei, Chen, Zhi-Wu, He, Guo-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201489/
https://ncbi.nlm.nih.gov/pubmed/30405745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8919867
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