Local Production of Soluble Urokinase Plasminogen Activator Receptor and Plasminogen Activator Inhibitor‐1 in the Coronary Circulation Is Associated With Coronary Endothelial Dysfunction in Humans

BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a proinflammatory biomarker associated with immune activation and fibrinolysis inhibition. Plasminogen activator inhibitor (PAI‐1) is associated with excessive fibrin accumulation, thrombus formation, and atherosclerosis. The re...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Corban, Michel T., Prasad, Abhiram, Nesbitt, Lisa, Loeffler, Darrell, Herrmann, Joerg, Lerman, Lilach O., Lerman, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201458/
https://ncbi.nlm.nih.gov/pubmed/30371230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009881
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