Variants at the APOE/C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High‐Density Lipoprotein Cholesterol

BACKGROUND: Macrophage cholesterol efflux to high‐density lipoproteins (HDLs) is the first step of reverse cholesterol transport. The cholesterol efflux capacity (CEC) of HDL particles is a protective risk factor for coronary artery disease independent of HDL cholesterol levels. Using a genome‐wide...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Low‐Kam, Cécile, Rhainds, David, Lo, Ken Sin, Barhdadi, Amina, Boulé, Marie, Alem, Sonia, Pedneault‐Gagnon, Valérie, Rhéaume, Eric, Dubé, Marie‐Pierre, Busseuil, David, Hegele, Robert A., Lettre, Guillaume, Tardif, Jean‐Claude
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201388/
https://ncbi.nlm.nih.gov/pubmed/30369316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009545
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