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Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1

Smoking is a major preventable risk factor for atherosclerosis. However, the causative link between cigarette smoke and atherosclerosis remains to be established. The objective of this study is to characterize the role of GTP cyclohydrolase 1 (GTPCH1), the rate‐limiting enzyme for de novo tetrahydro...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Li, Jingyuan, Liu, Shangming, Cao, Guangqing, Sun, Yuanyuan, Chen, Weiqian, Dong, Fajin, Xu, Jinfeng, Zhang, Cheng, Zhang, Wencheng
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201367/
https://ncbi.nlm.nih.gov/pubmed/30091833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13812
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