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A polymorphism rs3746444 within the pre‐miR‐499 alters the maturation of miR‐499‐5p and its antiapoptotic function

microRNAs (miRNAs) are non‐coding RNAs that function as post‐transcriptional regulators of cardiac development and cardiovascular diseases. Single nucleotide polymorphisms (SNPs) in miRNA genes are a novel class of genetic variations in the human genome that confer the risk of cardiovascular disease...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Ding, Wei, Li, Mengyang, Sun, Teng, Han, Di, Guo, Xiaoci, Chen, Xiao, Wan, Qinggong, Zhang, Xuejuan, Wang, Jianxun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201352/
https://ncbi.nlm.nih.gov/pubmed/30102014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13813
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