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“Crystal” clear? Lysophospholipid receptor structure insights and controversies

Lysophospholipids (LPLs), particularly sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA), are bioactive lipid modulators of cellular homeostasis and pathology. The discovery and characterization of five S1P- and six LPA-specific G protein-coupled receptors (GPCRs), S1P(1–5) and LPA(1–6),...

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Bibliografiske detaljer
Udgivet i:Trends Pharmacol Sci
Main Authors: Blaho, Victoria A., Chun, Jerold
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201317/
https://ncbi.nlm.nih.gov/pubmed/30343728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.08.006
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