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“Crystal” clear? Lysophospholipid receptor structure insights and controversies
Lysophospholipids (LPLs), particularly sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA), are bioactive lipid modulators of cellular homeostasis and pathology. The discovery and characterization of five S1P- and six LPA-specific G protein-coupled receptors (GPCRs), S1P(1–5) and LPA(1–6),...
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| Udgivet i: | Trends Pharmacol Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201317/ https://ncbi.nlm.nih.gov/pubmed/30343728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.08.006 |
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