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Carbapenem Resistance Caused by High-Level Expression of OXA-663 β-Lactamase in an OmpK36-Deficient Klebsiella pneumoniae Clinical Isolate

Carbapenem resistance is mainly mediated by carbapenemases or extended-spectrum β-lactamases (ESBL) plus a loss of porins. However, we have identified a Klebsiella pneumoniae clinical isolate that contains neither carbapenemases nor ESBLs. Instead, we found that high-level expression of a novel bla(...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ma, Peijun, Laibinis, Hannah H., Ernst, Christoph M., Hung, Deborah T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201135/
https://ncbi.nlm.nih.gov/pubmed/30126962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01281-18
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