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Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1
β-Lactam antibiotics are the mainstay for the treatment of bacterial infections. However, elevated resistance to these antibiotics mediated by metallo-β-lactamases (MBLs) has become a global concern. New Delhi metallo-β-lactamase-1 (NDM-1), a newly added member of the MBL family that can hydrolyze a...
Gardado en:
| Publicado en: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201099/ https://ncbi.nlm.nih.gov/pubmed/30150473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01579-18 |
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