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Mutational Evolution of Pseudomonas aeruginosa Resistance to Ribosome-Targeting Antibiotics

The present work examines the evolutionary trajectories of replicate Pseudomonas aeruginosa cultures in presence of the ribosome-targeting antibiotics tobramycin and tigecycline. It is known that large number of mutations across different genes – and therefore a large number of potential pathways –...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Sanz-García, Fernando, Hernando-Amado, Sara, Martínez, José L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200844/
https://ncbi.nlm.nih.gov/pubmed/30405685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00451
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