Early post-operative cognitive dysfunction after closed-loop versus manual target controlled-infusion of propofol and remifentanil in patients undergoing elective major non-cardiac surgery: Protocol of the randomized controlled single-blind POCD-ELA trial

INTRODUCTION: Post-operative cognitive dysfunction (POCD) is frequent in patients older than 60 years undergoing major non-cardiac surgery, and increases both morbidity and mortality. Anesthetic drugs may exert neurotoxic effects and contribute to the genesis of POCD. The hypothesis of the POCD-ELA...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Besch, Guillaume, Vettoretti, Lucie, Claveau, Melanie, Boichut, Nathalie, Mahr, Nicolas, Bouhake, Yannis, Liu, Ngai, Chazot, Thierry, Samain, Emmanuel, Pili-Floury, Sebastien
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200461/
https://ncbi.nlm.nih.gov/pubmed/30290615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000012558
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