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Single-molecule observation of nucleotide induced conformational changes in basal SecA-ATP hydrolysis

SecA is the critical adenosine triphosphatase that drives preprotein transport through the translocon, SecYEG, in Escherichia coli. This process is thought to be regulated by conformational changes of specific domains of SecA, but real-time, real-space measurement of these changes is lacking. We use...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Chada, Nagaraju, Chattrakun, Kanokporn, Marsh, Brendan P., Mao, Chunfeng, Bariya, Priya, King, Gavin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200364/
https://ncbi.nlm.nih.gov/pubmed/30397644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat8797
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