Differential Content of Proteins, mRNAs, and miRNAs Suggests that MDSC and Their Exosomes May Mediate Distinct Immune Suppressive Functions

Myeloid-derived suppressor cells (MDSC) are immature myeloid cells that accumulate in the circulation and the tumor microenvironment of most cancer patients. There, MDSC suppress both adaptive and innate immunity, hindering immunotherapies. The inflammatory milieu often present in cancers facilitate...

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Vydáno v:J Proteome Res
Hlavní autoři: Geis-Asteggiante, Lucía, Belew, Ashton T., Clements, Virginia K., Edwards, Nathan J., Ostrand-Rosenberg, Suzanne, El-Sayed, Najib M., Fenselau, Catherine
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200353/
https://ncbi.nlm.nih.gov/pubmed/29139296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00646
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