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Chymotrypsin Reduces the Severity of Secretagogue-induced Pancreatitis in Mice
Intra-pancreatic activation of the digestive proteases trypsin and chymotrypsin is an early event in the development of pancreatitis. Human genetic studies indicate that chymotrypsin controls trypsin activity via degradation, but there is no evidence of this from animal models. We used CRISPR-Cas9 t...
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| I publikationen: | Gastroenterology |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200337/ https://ncbi.nlm.nih.gov/pubmed/30076839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.06.041 |
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