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Chymotrypsin Reduces the Severity of Secretagogue-induced Pancreatitis in Mice

Intra-pancreatic activation of the digestive proteases trypsin and chymotrypsin is an early event in the development of pancreatitis. Human genetic studies indicate that chymotrypsin controls trypsin activity via degradation, but there is no evidence of this from animal models. We used CRISPR-Cas9 t...

詳細記述

保存先:
書誌詳細
出版年:Gastroenterology
主要な著者: Jancsó, Zsanett, Hegyi, Eszter, Sahin-Tóth, Miklós
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200337/
https://ncbi.nlm.nih.gov/pubmed/30076839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.06.041
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