Identification of a second binding site on the TRIM25 B30.2 domain

The retinoic acid-inducible gene-I (RIG-I) receptor recognizes short 5’-di- and triphosphate base-paired viral RNA and is a critical mediator of the innate immune response against viruses such as influenza A, Ebola, HIV and hepatitis C. This response is reported to require an orchestrated interactio...

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Veröffentlicht in:Biochem J
Hauptverfasser: D’Cruz, Akshay A., Kershaw, Nadia J., Hayman, Thomas J., Linossi, Edmond M., Chiang, Jessica J., Wang, May K., Dagley, Laura F., Kolesnik, Tatiana B., Zhang, Jian-Guo, Masters, Seth L., Griffin, Michael D.W., Gack, Michaela U., Murphy, James M., Nicola, Nicos A., Babon, Jeffrey J., Nicholson, Sandra E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200327/
https://ncbi.nlm.nih.gov/pubmed/29259080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170427
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