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Co-localization of plaque macrophages with calcification is associated with a more vulnerable plaque phenotype and a greater calcification burden in coronary target segments as determined by OCT

BACKGROUND: The presence of plaque macrophages and microcalcifications are acknowledged features of plaque vulnerability. Experimental data suggest that microcalcifications promote inflammation and macrophages foster microcalcifications. However, co-localization of plaque macrophages and calcificati...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Burgmaier, Mathias, Milzi, Andrea, Dettori, Rosalia, Burgmaier, Kathrin, Marx, Nikolaus, Reith, Sebastian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200236/
https://ncbi.nlm.nih.gov/pubmed/30356326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205984
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