Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1(I249/M280) Variant

Multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS) is the leading cause of non-traumatic neurological disability in young adults. Immune mediated destruction of myelin and oligodendrocytes is considered the primary pathology of MS, but progressive axon...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Cardona, Sandra M., Kim, Sangwon V., Church, Kaira A., Torres, Vanessa O., Cleary, Ian A., Mendiola, Andrew S., Saville, Stephen P., Watowich, Stephanie S., Parker-Thornburg, Jan, Soto-Ospina, Alejandro, Araque, Pedronel, Ransohoff, Richard M., Cardona, Astrid E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199958/
https://ncbi.nlm.nih.gov/pubmed/30386211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00365
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