A phase I–II controlled randomized trial using a promising novel cell-free formulation for articular cartilage regeneration as treatment of severe osteoarthritis of the knee

BACKGROUND: A promising novel cell-free bioactive formulation for articular cartilage regeneration, called BIOF2, has recently been tested in pre-clinical trials. The aim of the present study was to evaluate the efficacy and safety of BIOF2 for intra-articular application in patients with severe ost...

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Bibliografische gegevens
Gepubliceerd in:Eur J Med Res
Hoofdauteurs: Delgado-Enciso, Ivan, Paz-Garcia, Juan, Valtierra-Alvarez, Jose, Preciado-Ramirez, Jorge, Almeida-Trinidad, Roman, Guzman-Esquivel, Jose, Mendoza-Hernandez, Martha A., Garcia-Vega, Alberto, Soriano-Hernandez, Alejandro D., Cortes-Bazan, Jose L., Galvan-Salazar, Hector R., Cabrera-Licona, Ariana, Rodriguez-Sanchez, Iram P., Martinez-Fierro, Margarita L., Delgado-Enciso, Josuel, Paz-Michel, Brenda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199741/
https://ncbi.nlm.nih.gov/pubmed/30355362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-018-0349-2
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