Evaluation of aflibercept and ziv-aflibercept binding affinity to vascular endothelial growth factor, stability and sterility after compounding

PURPOSE: To investigate the binding affinity, stability, and sterility of aflibercept and ziv-aflibercept to vascular endothelial growth factor (Holash et al. in Proc Natl Acad Sci USA 99(17):11393–11398, 2002. 10.1073/pnas.172398299) after compounding and storage for up to 28 days at 4 °C and − 8 °...

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Bibliographic Details
Published in:Int J Retina Vitreous
Main Authors: de Lima Farah, Julia, Sano, Ronaldo, Maugéri, Ieda Maria Longo, Teixeira, Daniela, Ishimura, Mayari Eika, Martins, Gabriela, Mimica, Lycia M. J., da Silva, Cely Barreto, Meyer, Carsten H., de Oliveira Dias, João Rafael, de Andrade, Gabriel Costa, Farah, Michel Eid
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199727/
https://ncbi.nlm.nih.gov/pubmed/30386633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40942-018-0143-x
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