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Indirect Down-regulation of Tumor-suppressive let-7 Family MicroRNAs by LMO1 in Neuroblastoma

Background/Aim: Overall survival for the high-risk group of neuroblastoma (NB) patients still remains at 40-50%, necessitating the establishment of a curable treatment. LIM domain only 1 (LMO1) gene encoding a transcriptional regulator is an NB-susceptibility gene with a tumor-promoting activity. Pr...

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Bibliografske podrobnosti
izdano v:Cancer Genomics Proteomics
Main Authors: SAEKI, NORIHISA, SAITO, AKIRA, SUGAYA, YUKI, AMEMIYA, MITSUHIRO, SASAKI, HIROKI
Format: Artigo
Jezik:Inglês
Izdano: International Institute of Anticancer Research 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199578/
https://ncbi.nlm.nih.gov/pubmed/30194082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20100
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