Safety and efficacy of ixekizumab in patients with PsA and previous inadequate response to TNF inhibitors: week 52 results from SPIRIT-P2

OBJECTIVES: To assess the long-term safety and efficacy of ixekizumab, an IL-17A antagonist, in patients with active PsA. METHODS: In SPIRIT-P2 (NCT02349295), patients (n = 363) with previous inadequate response to TNF inhibitors entered the double-blind period (weeks 0–24) and received placebo or i...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: Genovese, Mark C, Combe, Benard, Kremer, Joel M, Tsai, Tsen-Fang, Behrens, Frank, Adams, David H, Lee, Chin, Kerr, Lisa, Nash, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Clinical Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199530/
https://ncbi.nlm.nih.gov/pubmed/30053162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/key182
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