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Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases
Phosphodiesterase-4 (PDE4), mainly present in immune cells, epithelial cells, and brain cells, manifests as an intracellular non-receptor enzyme that modulates inflammation and epithelial integrity. Inhibition of PDE4 is predicted to have diverse effects via the elevation of the level of cyclic aden...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6199465/ https://ncbi.nlm.nih.gov/pubmed/30386231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01048 |
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