Heterologous Immunization With Defined RNA and Subunit Vaccines Enhances T Cell Responses That Protect Against Leishmania donovani

The rapid generation of strong T cell responses is highly desirable and viral vectors can have potent CD8(+) T cell-inducing activity. Immunity to leishmaniasis requires selective T cell responses, with immunization schemes that raise either CD4 or CD8 T cell responses being protective in small anim...

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Udgivet i:Front Immunol
Main Authors: Duthie, Malcolm S., Van Hoeven, Neal, MacMillen, Zachary, Picone, Alessandro, Mohamath, Raodoh, Erasmus, Jesse, Hsu, Fan-Chi, Stinchcomb, Dan T., Reed, Steven G.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199377/
https://ncbi.nlm.nih.gov/pubmed/30386348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02420
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