Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway

Connexin 43 (Cx43) widely exists in all components of the neurovascular unit (NVU) and is a constituent of gap junctions and hemichannels. In physiological states, gap junctions are open for regular intercellular communication, and the hemichannels present low open probability in astrocytes. After c...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Chen, Yingzhu, Wang, Liangzhu, Zhang, Lingling, Chen, Beilei, Yang, Liu, Li, Xiaobo, Li, Yuping, Yu, Hailong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199357/
https://ncbi.nlm.nih.gov/pubmed/30386214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00372
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