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Inhibitory Receptors and Pathways of Lymphocytes: The Role of PD-1 in Treg Development and Their Involvement in Autoimmunity Onset and Cancer Progression

Regulatory T (Treg) cells represent a subpopulation of suppressor CD4(+) T cells critically involved in the establishment of peripheral tolerance through the inhibition of effector T (Teff) cells and the suppression of the immune-mediated tissue destruction toward self-antigens. Treg generation, the...

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Vydáno v:Front Immunol
Hlavní autoři: Gianchecchi, Elena, Fierabracci, Alessandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199356/
https://ncbi.nlm.nih.gov/pubmed/30386337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02374
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