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Inhibitory Receptors and Pathways of Lymphocytes: The Role of PD-1 in Treg Development and Their Involvement in Autoimmunity Onset and Cancer Progression
Regulatory T (Treg) cells represent a subpopulation of suppressor CD4(+) T cells critically involved in the establishment of peripheral tolerance through the inhibition of effector T (Teff) cells and the suppression of the immune-mediated tissue destruction toward self-antigens. Treg generation, the...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6199356/ https://ncbi.nlm.nih.gov/pubmed/30386337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02374 |
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