c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cells

Mesenchymal progenitor cells (MPCs) have been hypothesized as cells of origin for sarcomas, and c-Fos transcription factor has been showed to act as an oncogene in bone tumors. In this study, we show c-Fos is present in most sarcomas with chondral phenotype, while multiple other genes are related to...

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Pubblicato in:Sci Rep
Autori principali: Abarrategi, Ander, Gambera, Stefano, Alfranca, Arantzazu, Rodriguez-Milla, Miguel A., Perez-Tavarez, Raquel, Rouault-Pierre, Kevin, Waclawiczek, Alexander, Chakravarty, Probir, Mulero, Francisca, Trigueros, César, Navarro, Samuel, Bonnet, Dominique, García-Castro, Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199246/
https://ncbi.nlm.nih.gov/pubmed/30353072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33689-0
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