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Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip

EGFR mutations companion diagnostics have been proved to be crucial for the efficacy of tyrosine kinase inhibitor targeted cancer therapies. To uncover multiple mutations occurred in minority of EGFR-mutated cells, which may be covered by the noises from majority of un-mutated cells, is currently be...

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Bibliografske podrobnosti
izdano v:Nanomicro Lett
Main Authors: Li, Ren, Zhou, Mingxing, Li, Jine, Wang, Zihua, Zhang, Weikai, Yue, Chunyan, Ma, Yan, Peng, Hailin, Wei, Zewen, Hu, Zhiyuan
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199061/
https://ncbi.nlm.nih.gov/pubmed/30393665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40820-017-0168-y
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