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Association of common gene variants in glucokinase regulatory protein with cardiorenal disease: A systematic review and meta-analysis

BACKGROUND: Small-molecules that disrupt the binding between glucokinase and glucokinase regulatory protein (GKRP) in the liver represent a potential new class of glucose-lowering drugs. It will, however, take years before their effects on clinically relevant cardiovascular endpoints are known. The...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Simons, Pomme I. H. G., Simons, Nynke, Stehouwer, Coen D. A., Schalkwijk, Casper G., Schaper, Nicolaas C., Brouwers, Martijn C. G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198948/
https://ncbi.nlm.nih.gov/pubmed/30352097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206174
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