Creating and validating a warfarin pharmacogenetic dosing algorithm for Colombian patients

PURPOSE: Warfarin is an oral anticoagulant associated with adverse reaction to drugs due to wide inter- and intra-individual dosage variability. Warfarin dosage has been related to non-genetic and genetic factors. CYP2C9 and VKORC1 gene polymorphisms affect warfarin metabolism and dosage. Due to the...

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Detalhes bibliográficos
Publicado no:Pharmgenomics Pers Med
Main Authors: Galvez, Jubby Marcela, Restrepo, Carlos Martin, Contreras, Nora Constanza, Alvarado, Clara, Calderón-Ospina, Carlos-Alberto, Peña, Nidia, Cifuentes, Ricardo A, Duarte, Daniela, Laissue, Paul, Fonseca, Dora Janeth
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198877/
https://ncbi.nlm.nih.gov/pubmed/30410385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S170515
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