Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ(1–40) in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus

OBJECTIVE: This study was aimed at investigating whether sevoflurane inhalation induced cognitive impairment in rats with a possible mechanism involved in the event. METHODS: Thirty-two rats were randomly divided into four groups of normal saline (NS) + O(2), NS + sevoflurane (sevo), amyloid-β pepti...

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Опубликовано в: :Mediators Inflamm
Главные авторы: Tian, Yue, Chen, Ke-yan, Liu, Li-dan, Dong, Yun-xia, Zhao, Ping, Guo, Shan-bin
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2018
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198580/
https://ncbi.nlm.nih.gov/pubmed/30402039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3802324
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