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The balance of poly(U) polymerase activity ensures germline identity, survival and development in Caenorhabditis elegans
Poly(U) polymerases (PUPs) catalyze 3′ uridylation of mRNAs and small RNAs, a modification often correlating with decreased RNA stability. We have investigated the importance of three proteins with in vitro PUP activity, PUP-1/CDE-1, PUP-2 and PUP-3, in C. elegans germline development. Genetic analy...
Enregistré dans:
| Publié dans: | Development |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6198469/ https://ncbi.nlm.nih.gov/pubmed/30305273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.165944 |
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