High-fat, high-sugar diet induces splenomegaly that is ameliorated with exercise and genistein treatment

OBJECTIVE: We tested the effect of exercise training and genistein treatment on splenomegaly in mice fed a high-fat, high-sugar diet (HFSD). RESULTS: Male and female C57BL6 mice fed HFSD containing 60% fat along with drinking water containing 42 g/L sugar (55% sucrose/45% fructose) for 12 weeks exhi...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Buchan, Levi, St. Aubin, Chaheyla R., Fisher, Amy L., Hellings, Austin, Castro, Monica, Al-Nakkash, Layla, Broderick, Tom L., Plochocki, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Note
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198361/
https://ncbi.nlm.nih.gov/pubmed/30348225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3862-z
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