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Targeting immunotherapy for bladder cancer using anti‐CD3× B7‐H3 bispecific antibody

OBJECTIVE: B7‐H3 is attractive for cancer immunotherapy with B7‐H3 overexpressed tumors. To explore whether B7‐H3 is an effective target for patients with bladder cancer, anti‐CD3× anti‐B7‐H3 bispecific antibodies (B7‐H3Bi‐Ab) was armed with activated T cells (ATC) to kill bladder cancer cells. METH...

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Publicado en:Cancer Med
Autores principales: Ma, Wanru, Ma, Juan, Ma, Ping, Lei, Ting, Zhao, Man, Zhang, Man
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198238/
https://ncbi.nlm.nih.gov/pubmed/30253078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1775
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