CSF1R Inhibition Reduces Microglia Proliferation, Promotes Tissue Preservation and Improves Motor Recovery After Spinal Cord Injury

Spinal cord injury (SCI) induces a pronounced neuroinflammation driven by activation and proliferation of resident microglia as well as infiltrating peripheral monocyte-derived macrophages. Depending on the time post-lesion, positive and detrimental influences of microglia/macrophages on axonal rege...

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Опубликовано в: :Front Cell Neurosci
Главные авторы: Gerber, Yannick Nicolas, Saint-Martin, Guillaume Patrick, Bringuier, Claire Mathilde, Bartolami, Sylvain, Goze-Bac, Christophe, Noristani, Harun Najib, Perrin, Florence Evelyne
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198221/
https://ncbi.nlm.nih.gov/pubmed/30386212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00368
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