Force‐frequency relationship and early relaxation kinetics are preserved upon sarcoplasmic blockade in human myocardium

In this study, we investigated the quantitative and qualitative role of the sarcoplasmic reticulum (SR) in the regulation of the force‐frequency relationship (FFR). We blocked the function of SR with cyclopiazonic acid (CPA) and ryanodine and measured twitch kinetics and developed force at various s...

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Vydáno v:Physiol Rep
Hlavní autoři: Chung, Jae‐Hoon, Canan, Benjamin D., Whitson, Bryan A., Kilic, Ahmet, Janssen, Paul M. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198135/
https://ncbi.nlm.nih.gov/pubmed/30350481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13898
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