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Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli

Immunoglobulin light chain amyloidosis is the most common form of systemic amyloidosis. However, very little is known about the underlying mechanisms that initiate and modulate the associated protein aggregation and deposition. Model systems have been established to investigate these disease-associa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hand, Kieran, Wilkinson, Mark C., Madine, Jillian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197867/
https://ncbi.nlm.nih.gov/pubmed/30347409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206167
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