Inhibition of miR-449a Promotes Cartilage Regeneration and Prevents Progression of Osteoarthritis in In Vivo Rat Models

Traumatic and degenerative lesions of articular cartilage usually progress to osteoarthritis (OA), a leading cause of disability in humans. MicroRNAs (miRNAs) can regulate the differentiation of human bone marrow-derived mesenchymal stem cells (hBMSCs) and play important roles in the expression of g...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Baek, Dawoon, Lee, Kyoung-Mi, Park, Ki Won, Suh, Jae Wan, Choi, Seong Mi, Park, Kwang Hwan, Lee, Jin Woo, Kim, Sung-Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197768/
https://ncbi.nlm.nih.gov/pubmed/30326428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.09.015
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