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Long non-coding RNA LINC-01572:28 inhibits granulosa cell growth via a decrease in p27 (Kip1) degradation in patients with polycystic ovary syndrome

BACKGROUND: Disordered folliculogenesis is a key feature of polycystic ovary syndrome (PCOS), but the underlying molecular mechanism remains unclear. METHODS: Long non-coding RNA (lncRNA) expression in luteinized granulosa cells (hLGCs) derived from women with and without PCOS were analyzed using mi...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zhao, Jun, Xu, Jieying, Wang, Wangshen, Zhao, Han, Liu, Hongbin, Liu, Xiaojing, Liu, Jiansheng, Sun, Yun, Dunaif, Andrea, Du, Yanzhi, Chen, Zi-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197751/
https://ncbi.nlm.nih.gov/pubmed/30293818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.043
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