Fisetin is a senotherapeutic that extends health and lifespan

BACKGROUND: Senescence is a tumor suppressor mechanism activated in stressed cells to prevent replication of damaged DNA. Senescent cells have been demonstrated to play a causal role in driving aging and age-related diseases using genetic and pharmacologic approaches. We previously demonstrated that...

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Publicado en:EBioMedicine
Autores principales: Yousefzadeh, Matthew J., Zhu, Yi, McGowan, Sara J., Angelini, Luise, Fuhrmann-Stroissnigg, Heike, Xu, Ming, Ling, Yuan Yuan, Melos, Kendra I., Pirtskhalava, Tamar, Inman, Christina L., McGuckian, Collin, Wade, Erin A., Kato, Jonathon I., Grassi, Diego, Wentworth, Mark, Burd, Christin E., Arriaga, Edgar A., Ladiges, Warren L., Tchkonia, Tamara, Kirkland, James L., Robbins, Paul D., Niedernhofer, Laura J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197652/
https://ncbi.nlm.nih.gov/pubmed/30279143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.015
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