l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism

OBJECTIVE: AMP activated protein kinase (AMPK) is recognized as an important nutrient sensor contributing to regulation of cellular, tissue, and systemic metabolism. We aimed to identify specific amino acids which could modulate AMPK and determine effects on cellular and systemic metabolism. METHODS...

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Опубликовано в: :Mol Metab
Главные авторы: Adachi, Yusuke, De Sousa-Coelho, Ana Luisa, Harata, Ikue, Aoun, Charlie, Weimer, Sandra, Shi, Xu, Gonzalez Herrera, Karina N., Takahashi, Hirokazu, Doherty, Chris, Noguchi, Yasushi, Goodyear, Laurie J., Haigis, Marcia C., Gerszten, Robert E., Patti, Mary-Elizabeth
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197624/
https://ncbi.nlm.nih.gov/pubmed/30190193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.08.002
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