l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism

OBJECTIVE: AMP activated protein kinase (AMPK) is recognized as an important nutrient sensor contributing to regulation of cellular, tissue, and systemic metabolism. We aimed to identify specific amino acids which could modulate AMPK and determine effects on cellular and systemic metabolism. METHODS...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Adachi, Yusuke, De Sousa-Coelho, Ana Luisa, Harata, Ikue, Aoun, Charlie, Weimer, Sandra, Shi, Xu, Gonzalez Herrera, Karina N., Takahashi, Hirokazu, Doherty, Chris, Noguchi, Yasushi, Goodyear, Laurie J., Haigis, Marcia C., Gerszten, Robert E., Patti, Mary-Elizabeth
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197624/
https://ncbi.nlm.nih.gov/pubmed/30190193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.08.002
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