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Dynamic DNA methylation: in the right place at the right time
The classical model of cytosine DNA methylation (5mC) regulation depicts this covalent modification as a stable repressive regulator of promoter activity. However, whole genome analysis of 5mC reveals more widespread tissue and cell type-specific patterns, and pervasive dynamics during mammalian dev...
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| Publicado en: | Science |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6197482/ https://ncbi.nlm.nih.gov/pubmed/30262495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat6806 |
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