GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition

We previously reported that overexpression of an O-type glycosyltransferase, GALNT6 (polypeptide N-acetylgalactosaminyltransferase 6) played critical roles in mammary carcinogenesis. To further investigate the biological function of GALNT6, we screened a substrate protein(s) of GALNT6 using a VVA (V...

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Détails bibliographiques
Publié dans:Neoplasia
Auteurs principaux: Lin, Jiaying, Chung, Suyoun, Ueda, Koji, Matsuda, Koichi, Nakamura, Yusuke, Park, Jae-Hyun
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press 2017
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Original article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197318/
https://ncbi.nlm.nih.gov/pubmed/28110670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.11.007
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