GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition

We previously reported that overexpression of an O-type glycosyltransferase, GALNT6 (polypeptide N-acetylgalactosaminyltransferase 6) played critical roles in mammary carcinogenesis. To further investigate the biological function of GALNT6, we screened a substrate protein(s) of GALNT6 using a VVA (V...

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Detalles Bibliográficos
Publicado en:Neoplasia
Main Authors: Lin, Jiaying, Chung, Suyoun, Ueda, Koji, Matsuda, Koichi, Nakamura, Yusuke, Park, Jae-Hyun
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2017
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Original article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197318/
https://ncbi.nlm.nih.gov/pubmed/28110670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.11.007
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