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Gene Therapy for Hemoglobinopathies

Gene therapy for β-thalassemia and sickle-cell disease is based on transplantation of genetically corrected, autologous hematopoietic stem cells. Preclinical and clinical studies have shown the safety and efficacy of this therapeutic approach, currently based on lentiviral vectors to transfer a β-gl...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Cavazzana, Marina, Mavilio, Fulvio
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196755/
https://ncbi.nlm.nih.gov/pubmed/30200783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.122
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