Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis

γδ T cells are enriched at barrier sites such as the gut, skin, and lung, where their roles in maintaining barrier integrity are well established. However, how these cells contribute to homeostasis at the gingiva, a key oral barrier and site of the common chronic inflammatory disease periodontitis,...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Krishnan, Siddharth, Prise, Ian E., Wemyss, Kelly, Schenck, Louis P., Bridgeman, Hayley M., McClure, Flora A., Zangerle-Murray, Tamsin, O’Boyle, Conor, Barbera, Thomas A., Mahmood, Faiza, Bowdish, Dawn M. E., Zaiss, Dietmar M. W., Grainger, John R., Konkel, Joanne E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196490/
https://ncbi.nlm.nih.gov/pubmed/30279177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802320115
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