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Src kinase phosphorylates Notch1 to inhibit MAML binding

Notch signaling is a form of intercellular communication which plays pivotal roles at various stages in development and disease. Previous findings have hinted that integrins and extracellular matrix may regulate Notch signaling, although a mechanistic basis for this interaction had not been identifi...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: LaFoya, Bryce, Munroe, Jordan A., Pu, Xinzhu, Albig, Allan R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195628/
https://ncbi.nlm.nih.gov/pubmed/30341382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33920-y
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