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Genome wide mapping of ETV6 binding sites in pre-B leukemic cells

Genetic alterations in the transcriptional repressor ETV6 are associated with hematological malignancies. Notably, the t(12;21) translocation leading to an ETV6-AML1 fusion gene is the most common genetic alteration found in childhood acute lymphoblastic leukemia. Moreover, most of these patients al...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Neveu, Benjamin, Caron, Maxime, Lagacé, Karine, Richer, Chantal, Sinnett, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195514/
https://ncbi.nlm.nih.gov/pubmed/30341373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33947-1
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