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Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk

Most vaccines depend on co-administration of antigens and adjuvants that activate antigen-presenting cells (APCs). Nanoparticles (NPs) have emerged as an attractive vehicle for synchronized delivery of antigens and adjuvants to APCs and can be targeted to specific cell types such as dendritic cells...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Sehgal, Kartik, Ragheb, Ragy, Fahmy, Tarek M., Dhodapkar, Madhav V., Dhodapkar, Kavita M.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195217/
https://ncbi.nlm.nih.gov/pubmed/25080481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400489
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