Inter-tumoral heterogeneity in SCLC is influenced by the cell-type of origin

The extent to which early events shape tumor evolution is largely uncharacterized, even though a better understanding of these early events may help identify key vulnerabilities in advanced tumors. Here, using genetically defined mouse models of small cell lung cancer (SCLC), we uncovered distinct m...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Yang, Dian, Denny, Sarah K., Greenside, Peyton G., Chaikovsky, Andrea C., Brady, Jennifer J., Ouadah, Youcef, Granja, Jeffrey M., Jahchan, Nadine S., Lim, Jing Shan, Kwok, Shirley, Kong, Christina S., Berghoff, Anna S., Schmitt, Anna, Reinhardt, H. Christian, Park, Kwon-Sik, Preusser, Matthias, Kundaje, Anshul, Greenleaf, William J., Sage, Julien, Winslow, Monte M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195211/
https://ncbi.nlm.nih.gov/pubmed/30228179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-17-0987
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