Inhibition of peptidylarginine deiminase alleviates LPS-induced pulmonary dysfunction and improves survival in a mouse model of lethal endotoxemia

Immune cell death caused by neutrophil extracellular traps (NETs), referred to as NETosis, can contribute to the pathogenesis of endotoxemia and organ damage. Although the mechanisms by which infection induces NETosis and how that leads to organ dysfunction remain largely unknown, NET formation is o...

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發表在:Eur J Pharmacol
Main Authors: Liang, Yingjian, Pan, Baihong, Alam, Hasan B., Deng, Qiufang, Wang, Yibing, Chen, Eric, Liu, Baoling, Tian, Yuzi, Williams, Aaron, Duan, Xiuzhen, Wang, Yanming, Zhang, Jifeng, Li, Yongqing
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195118/
https://ncbi.nlm.nih.gov/pubmed/29981294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2018.07.005
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